One lane on southbound I-294 reopened about 11 a.m. Tuesday after a crash involving a semitrailer at the Golf Road Toll Plaza.
Two people were hurt in the single-vehicle crash at 8 a.m., according to Illinois State Police. Their injuries were not life-threatening.
All three southbound lanes were initially closed for three hours, state police said. The two right lanes remain closed.
It was not immediately clear what caused the crash.