CHICAGO - Lucas Giolito struck out 12 and the Chicago White Sox sent Baltimore to its 13th straight loss, beating the Orioles 3-1.
The Orioles matched their worst skid since 2009. Baltimore's all-time longest losing streak was 21 in a row in 1988.
Baltimore has been swept in four consecutive series and dropped 20 of 22 overall.
Nick Madrigal hit a tiebreaking triple in the seventh inning as the White Sox completed a four-game sweep.
The AL Centrals have won six of seven and climbed a season-high 12 games over .500.