Darlene Cruz, 47, was last seen on Aug. 31 on South Trumball in Little Village.
She might be driving her white Nissan Maxima, with Illinois license plate CC81369.
She may need medical attention.
Cruz is a white woman, 5'3", 180 pounds, with brown eyes and black hair. She has a tattoo on her left hand on her ring finger and another tattoo on a forearm.