The man became involved in a verbal altercation with a woman in the courtyard of a building about 4:11 a.m. in the 2700 block of West 75th Place, Chicago police said.
The woman struck the man over the head with a bottle and then stabbed him multiple times with the broken battle.
SWAT teams responded after the woman barricaded herself inside a residence.
The man was transported to University of Chicago Hospital with multiple lacerations. His condition was not immediately known.
No one is currently in custody.