About 8:41 a.m., the transit agency reported inbound train #704 derailed near the LaSalle Street station, according to Metra spokesman Michael Gillis.
The train was carrying about 600 passengers, but there were no reported injuries, according to the Chicago fire officials.
Trains behind #704 were stopped near 35th Street, where passengers were able to board the CTA Red Line train, Gillis said. CTA will honor Metra tickets for passengers boarding at the 35th Street station.
As of 3:10 p.m., Metra was operating limited outbound service on the Rock Island line for the evening rush hour, with delays up to 30 minutes possible.
Inbound service remains suspended until further notice.
Metra officials encouraged passengers to use alternative lines including Metra Electric, Southwest Service and Heritage Corridor.
The cause of the derailment remains under investigation.
FULL METRA ROCK ISLAND OUTBOUND SERVICE SCHEDULE FOR AUGUST 28
The Sun-Times Media Wire contributed to this report.